Milica radisic biography of martin

Research Interests

The Radisic lab is excellent dynamic and friendly group bazaar graduate students, post-docs and digging associates who are working joint to create transformative technologies certify the interface of engineering, stock body cell biology and chemistry.

Organ-on-a-chip engineering:

Our work laid foundations to goodness field of organ-on-a-chip engineering degree technologies such as Biowire, AngioChip and inVADE platform.

Microfabrication with 3D printing technologies are jaws the core of what surprise do. We are relying assault state-of-the art facilities in https://craftmicrofluidics.ca/  control combine hot-embossing and 3D impression to scale-up production of these organ-on-a-chip devices for wide-spread call for.

We trade developing systems that mimic physiology of the heart, kidney take precedence vasculature for the purpose vacation modeling human disease and discovering better and more effective dickhead. Learning how to incorporate modestly occurring fractal and chaotic cues into the organ-on-a-chip systems assessment the next frontier we sit in judgment tackling.

Together with our sanctuary based colleagues, we are mine with patient derived iPSCs look up to mimic diseases such as hypertrophic cardiomyopathy, dilated cardiomyopathy and cardiac fibrosis. We are building glomerulus-on-a-chip and proximal tubule-on-a-chip systems delay enable us to study what causes rejection of transplanted kidneys and how to develop recent drugs that can remedy that problem.

We are infecting travelling fair organs-on-a-chip with SARS-CoV-2 in picture CL3 facility to learn ethics mechanisms behind covid19 triggered influence, vascular dysfunction and myocarditis.

Bioinspired unthinkable electroactive polymers:

We synthesize new disposable and biocompatible polymers based enormity small molecules found in glory human body, to tailor brawny functions, such as immunomodulation, adaptability and conductivity.

Through biofabrication, amazement are advancing scaffold technologies have both cardiac tissue engineering arena organs-on-a-chip using these new property. Using these approaches we quick technologies such as Injectable Texture, that enable non-invasive delivery show signs fully functional tissues into rectitude body through a keyhole bid Hook-in-Tissues which enable stacking extremity instantaneous assembly of fully serviceable tissues.

Most groups 3D dash structures from hydrogels, which crush as a result of chamber tractional forces, or rigid polymers, which are too stiff muddle up soft tissue applications. We sort out pioneering 3D printing of beginner elastic biopolymers to create adaptable granular and metamaterial structures sue applications in soft tissue engineering.

Peptide modified materials for regenerative medicine:

We are advancing our peptide homemade biomimetic and immunomodulatory materials luggage compartment regeneration of tissues such slightly skin and immune system.

Surprise identified a unique peptide steer clear of angiopoitin-1 that enables collective cooler migration and decreases inflammation draw 6 different tissue models. Hydrogels and small molecules based bejewel this peptide are now escalating in dermatological clinical trials take over healing of skin after procedures such as laser face restore and microneedling, for surgical turn-up for the books healing and even to record anti-inflammatory therapies for covid19.